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Ibutamoren/MK-677
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Ibutamoren/MK-677

Browse:292 Date:2019-03-22 Font Size:Big Medium Small
Ibutamoren/MK-677
Ibutamoren/MK-677
CAS :159752-10-0
Formula: C28H40N4O8S2
Molecular Weight : 624.77
Boiling Point : 868.9 °C at 760 mmHg
Flash Point : 479.3 °C
Other Name : Crescendo, UNII-R90JB6QJ2B
Appearance : powder
Purity : ≥ 99.0%
 
MK677 Benefits and effects
1) Ibutamoren promotes muscle growth
Ibutamoren is often used as an anabolic substance to increase muscle mass. Its principle is to use ibutamoren to increase the body's growth hormone (HGH) and IGF-1 secretion. And growth hormone (hgh) just can increase and improve muscle mass, strength and accelerate the consumption of body fat; while IGF-1 reduces muscle damage and thus protects the health of muscles. Therefore, using ibutamoren can increase the body's strength and muscle growth potential for long term. It is said that muscles can grow up to 6 pounds in only 8 weeks. This is an wonderful result. In the past, IGF-1 had to be injected everyday. It was very expensive and very painful. It  needs oral to be instead now.
2)Ibutamoren is benifit for weight loss.
Higher purity of HGH can increase fat burning and lead to greater fat loss. HGH also helps to maintain muscle mass while reducing calories. This is because of better nutrient absorption and using.
Studies have found that the using of ibutamoren has decreased the fat content of several obese men for a period of two months . At the same time, diet weight loss volunteers in the weight loss experiment showed that protein loss was reversed during dieting using ibutamoren, which may lead to muscle atrophy, but can prevent muscle atrophy from using ibutamoren.
3)Ibutamoren can go up bone density
Another benefit of HGH to improve nutrient metabolism is to improve bone health. Higher levels hgh are associated with higher bone density and development.
This means that supplementing of MK-677 can help prevent stress fractures in which athletes are injured. It can also be used to prevent osteoporosis and reduce fractures in the elderly.
In healthy obese male volunteers, using ibutamoren to lose weight not only consumers fat but also increases bone density.
This helps increase bone strength and prevent osteoporosis.
4)Ibutamoren  improves sleep
One study showed that ibutamoren improved sleep quality and accelerated sleep time among young and old people.
Good restorative sleep can allow you to perform better in the fitness process.
5)Ibutamoren has the functions for anti-aging, improves skin tone, and may prolong life.
Growth hormone (HGH) secretion and muscle mass are all decreased from the middle of puberty. Higher levels of HGH help promote the growth and recovery of older cells in combination with the anti-inflammatory effects of IGF-1 to help maintain cell health and prevent breakdown. At the same time, higher levels of IGF-1 may help maintain the development of brain material. Ibutamoren just activates growth hormone (hgh) and IGF-1 so as to achieve anti-aging, improve skin tone, and possibly prolong life.
 
ibutamoren可以改善大脑功能的两种间接机制:
Ibutamoren增加IGF-1 ,这已知可以改善记忆和学习。
6)Ibutamoren may have nootropic effect
Some people use ibutamoren as a psychoactive drug because it acts on the ghrelin receptor, which has a nootropic effect. However, science still studies whether and how to use ibutamoren to influence cognitive ability.
Ibutamoren can improve two indirect mechanisms of brain function:
Ibutamoren can increases IGF-1, which is known to improve memory and learning.
Ibutamoren also increase sleep time and improve sleep quality. We know that sleep is essential for good cognitive function.
The above are only indirect speculations and have not been confirmed.
7)Ibutamoren can help wound healing and tissue regeneration
Growth hormone (hgh) increases tissue regeneration and wound healing, so ibutamoren may contribute to these items.
Through the above benefits we can know: Ibutamoren (Mk-677) increases growth hormone (HGH) and IGF-1 levels,
Burn fat, building muscles, tighten loose skin, improve sleeping, increase bone density and so on.
Although Ibutamoren has so many benefits but it can increase muscle mass and increase muscle strength. The Anti-doping body may consider it a "prohibited substance" and test it when evaluating high-level athletes. Therefore, most of the purchasers are made in the name of scientific research.
How does is work?
Basically, the active ingredient in the supplement binds to the ghrelin receptor in the body. This leads to an increase in the amount of somatotropin that results in the release of pituitary in the brain. It does this while keeping Cortisol intact. Hormones such as insulin growth factor (IGF-1) increase in metabolism in the liver and other tissues. Theory speaking, MK-677 should be an ideal supplement for those who want to improve their health and fitness. Athletes who wish to gain more benefits from training may also be helpful.
Dose:
In every study, oral doses of 25 mg once a day were given to healthy youth, and after 7 days of this dose, the subjects showed a continuous increase in serum concentrations of IGF-1 and growth hormone. In addition, the state of protein loss caused by dieting was reversed. The study gave the subject 25 mg of Nutrobal daily for 8 weeks. Subjects showed increased basal metabolic rate after 2 weeks and increased HGH, IGF-1 and IGF-1 binding protein levels.
Studies have shown that oral doses of 25 mg is reasonable.
Week  Mk-677 GW-501516 Anrdarine(S-4)  HCGenerateES N2Guard
1 25mgs/ED 20mgs/ED 35mgs/ED 5tabs/ED 5caps/ED
2 25mgs/ED 20mgs/ED 35mgs/ED 5tabs/ED 5caps/ED
3 25mgs/ED 20mgs/ED 45mgs/ED 5tabs/ED 5caps/ED
4 25mgs/ED 20mgs/ED 45mgs/ED 5tabs/ED 5caps/ED
5 25mgs/ED 20mgs/ED 50mgs/ED 5tabs/ED 5caps/ED
6 25mgs/ED 20mgs/ED 50mgs/ED 3tabs/ED 5caps/ED
7 25mgs/ED 20mgs/ED 60mgs/ED 3tabs/ED 5caps/ED
8 25mgs/ED 20mgs/ED 60mgs/ED 2tabs/ED 5caps/ED
9 25mgs/ED 20mgs/ED 70mgs/ED 2tabs/ED 5caps/ED
Supplements should also be accompanied by high quality diet and training programs to maximize results.
This diet will include high protein, adequate vitamins and minerals, and healthy fats. At the same time, various sport-specific training programs should be conducted. This should include weight training and proper aerobic exercise.
 
What should I pay attention to?
side effect:
1. The most commonly side effects of ibutamoren are appetite and transient increase, slight lower extremity edema and muscle pain.
2. Some studies have reported increased fasting glucose and decreased insulin sensitivity. These side effects are similar to those with elevated levels of growth hormone, mainly joint pain and insulin resistance.
3. Although most studies reported little or no side effects, one study was terminated due to serious adverse events. In elder hip fracture patients, ibutamoren can increased blood pressure, blood glucose and HbA1c, and had congestive heart failure. Patients experiencing congestive heart failure are over 80 years old and have a history of previous heart failure.
4. The sensitivity of the hypothalamus-pituitary axis is reduced.
5. The effect of prolactin.
How to prevent the side effects?
 
It is one of the safer and soft HGH release products in the market. However, it must not be used for long terms.
Pay more attention the 3,4,5 items
 
As to the third item, it is sufficient to know the physical condition of oneself and choose whether to use it according to the actual situation.
Pay close attention to the side effects of the fifth point. If you use it for a long period of time, one problem that may arise is the decreased sensitivity of the hypothalamus-pituitary axis. This basically means that the hypothalamus and pituitary receptors will not receive the mk677 stimulus. This means that it will stop releasing HGH, which may eventually lead to the release of HGH. Even after the replenishment stops, this situation may still continue to occur. To avoid this situation, the use of supplements should be recycled.
The impact of prolactin on point 5, another potential problem with taking a higher dose of MK-677 is its effect on prolactin. This hormone is often known for promoting women's milk. However, it may cause testosterone and estrogen levels to decline, suppress the immune system, and may affect mood. Therefore, keeping the dose within the recommended range can help prevent any problems associated with high prolactin levels. This will ensure that your cycle is as effective and enjoyable as possible.
Meanwhile, the user carefully observes carbohydrate intake and regularly checks blood glucose and insulin levels as anabolics. If suffering from cancer, ibutamoren should be avoided. Both growth hormone and IGF-1 may promote the growth of cancer.
Our company is the largest API manufacturer of mk677 in China.Our production of mk-677 has a history of 5 years, and all production mk-677 raw materials have a purity of more than 99% and each batch has HPLC and NMR detection reports.The mk677 monthly output is 50kg and the quality is stable.
The mk677 powder produced by our company is mainly supplied to Canada and its European market, and the customer feedback is good. Our company is a leading supplier of health care products, research institutes and fitness enthusiasts.
The mk677 provided by our company is powder, the color is white to light yellow, the standard package is 1 kg/aluminum foil bag.We also can be divided into smaller package for the customer.The order is unlimited.After customers purchase, they can be directly processed into tablets and liquids.
 It would be the best choice to cooperate with us,due to we have below advantages.
1. Professional.We has developed and produced sram series for 5 years.Rich experience in production, stable product quality, product purity up to 99%.
2. Formal business.Our company can provide HPLC, nuclear magnetic and other professional detection map for each batch of products.
3. Fast delivery. Products will send out within 24hours,delivery time is 7-10days.
4. Good service. We will provide the most thoughtful service, from procurement, quality inspection, delivery to application, etc.
How to make MK677 product quality firs in the industry
At the beginning of the development of mk677,Our company established the objective of making the quality of mk677 to be first in the industry..
There are two guarantees:
The first, the synthesis route of MK-677 is the best.
After a long period of research and development optimization, we have established the optimal route from numerous small trials and pilot trials to the last big test. Select the optimal route, and then make the purity of MK-677 to the highest, At last make the quality to be first by letting it through the column of repeated purification
Second, mk677 is strictly tested.
Each batch of production of MK-677 will be strictly tested. Through nuclear magnetic, HPLC detection and other methods to ensure that every batch of delivery to customers is no problem.
The impurity of MK-677 control
The substances that affect the purity of mk677 are called impurities.
Source of impurities.
1. Organic impurities introduced in MK677 production process;
2. In the purification process of MK-877 residual inorganic impurities and residual solvents. 3. 3. The decomposition of MK-677 products produced during storage.
These impurities can affect the purity of MK677, so the control of impurities is an important a spect of MK-677 research..
Therefore, we have established a strong and sensitive analytical method for strict control of impurities.
How to order MK677:
First of all, Please confirm that the quantity you need to purchase. Let us know you want to purchase the product by company or individuals. You may send your information to us via email&skype and phone. we will reply as soon as possible.
If the customer purchases a large number of products and needs to be inspected after purchasing, we can provide free sample for testing. The freight to foreign countries is borne by the customer is 60usd.
Full 1500 US Dollars Worldwide Shipping Less than 1,500 US dollars Customers need to provide 60 US dollars freight.If you order the cost exceed 1500usd, the shipping cost is free. If not, you need pay for 60usd shipping cost.
 
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